The Surprising Thing which May Lower Your Chance of IVF Success
New research shows that depression and anxiety can be associated with a reduced chance of pregnancy after IVF.
Here is some amazing news if you are a female who is anxious or depressed and planning to undergo fertility treatments: According to a new study- depression-and anxiety, and not necessarily the use of antidepressants can be linked with a reduced opportunity of getting pregnant after IVF.
Until now, little has been known about the effect of antidepressants on fertility –and the ability to get pregnant. This study, that involved more than 23,000 ladies, is the largest so far to look for connections. Researchers usually used data on all IVF procedures performed in Sweden from 2007 till present, then linked it to information on depression, anxiety, antidepressant prescriptions from the Swedish Patient and also Prescribed Drug Registers.
A little more than 4% of the ladies in the study had depression or anxiety diagnosis in the 2 years before the start of their IVF cycle –and/or an antidepressant dispensation in the 6 months before. So the researchers compared the rates of pregnancy, live birth, and miscarriage in these ladies to the rates in ladies who didn’t have a diagnosis or antidepressant dispensation.
“We found that ladies undergoing their 1st IVF treatment who either had been diagnosed with depression/anxiety/had been dispensed an antidepressant had lower rates of pregnancy and also live birth rates compared to women who didn’t suffer from like these conditions or take antidepressants before beginning their IVF treatment,” said study author Carolyn Cesta. “Importantly, we found that ladies with a depression or anxiety diagnosis without a prescription of antidepressants had an even lower opportunity of getting pregnant or having a live birth.”
And here is something else: In the group of female taking SSRIs (the most commonly prescribed type of antidepressant), there was no difference in pregnancy/ live birth rates following IVF treatment. But the group of ladies taking antidepressants which were not SSRIs, and also who had more complex cases of depression and anxiety, showed reduced odds of pregnancy and live birth as well as an increased risk for miscarriage following their IVF treatment.
“Taken together, results indicate that the depression and anxiety diagnoses can be the underlying factor leading to lower pregnancy chance and live birth rates in these ladies,” said Dr. Anastasia Nyman Iliadou, The associate professor at the Department of Medical Epidemiology and also Biostatistics. She cautioned, however, that the results would also be explained by “unmeasured lifestyle and/or genetic factors associated with depression and anxiety.”
What this means is, until there is more conclusive evidence, you should speak to your personal doctor if you are trying to conceive and have symptoms of depression or anxiety, or are currently taking antidepressant medicines.